Gh. Lipscomb et al., THE EFFECT OF NITROUS-OXIDE AND CARBON-DIOXIDE PNEUMOPERITONEUM ON POSTLAPAROSCOPY TUBAL-LIGATION PAIN, Journal of gynecologic surgery, 9(3), 1993, pp. 175-178
No study has investigated objectively the effects of various pneumoper
itoneum gases on postlaparoscopy pain. The purpose of this study was t
o compare objectively the effect of carbon dioxide and nitrous oxide p
neumoperitoneum on postlaparoscopic pain. Patients undergoing laparosc
opic tubal ligation under general anesthesia were randomized to carbon
dioxide (n = 24) or nitrous oxide (n = 29) pneumoperitoneum. A modifi
ed McGill pain questionnaire was used to assess postlaparoscopic pain
at 15 min, 1 h, and 25 h postoperatively. The demographics and surgica
l characteristics of each group were comparable except for patient wei
ght. There was no difference between the groups in postoperative analg
esic requirements or pain ratings for each studied time period. Based
on these results, nitrous oxide pneumoperitoneum does not appear to pr
oduce less postlaparoscopic pain than carbon dioxide pneumoperitoneum.