THE SIGNIFICANCE OF AUTOGENOUS INFECTION IN DEVELOPMENT OF POSTOPERATIVE COMPLICATIONS

The authors studied the mechanisms of bacterial dissemination in opera tive wounds in patients after various surgical interventions. It was d emonstrated in experiments that during adaptation of the organism to t he operative stress, autobacteria enter the blood from the intestinal reservoir and are eliminated through the urinary tract and wound surfa ces, if foci of mechanical or toxic destruction exist the autobacteria precipitate in the affected tissues and participate directly in the r eparative processes. On the basis of the obtained data it is suggested that the phenomenon of activation and persistence of endogenous micro flora exists as one of the syndromes of adaptation of man to the aggre ssion factor, which is aimed at revealing and removing the foci of tis sue destruction developing as the result of exposure to the effect of the stress.