A CASE OF SEVERE IGA NEPHROPATHY ASSOCIATED WITH PSORIATIC-ARTHRITIS AND IDIOPATHIC INTERSTITIAL PNEUMONIA

A patient is described with severe IgA nephropathy associated with pso riatic arthritis, idiopathic interstitial pneumonia and brain hemorrha ge that developed serially over one and a half years. The histological findings of the renal biopsy showed severe endo- and extracapillary p roliferative glomerulonephritis. Massive IgA deposits were observed by immunofluorescence not only in the mesangium but also along the capil lary walls. Electron microscopy revealed abundant electron-dense depos its in the mesangial and subendothelial areas. The overlapping or coex istence of these conditions has rarely been reported.