H. Oguni et al., ELECTROENCEPHALOGRAPHIC FEATURES OF EPILEPTIC DROP ATTACKS AND ABSENCE SEIZURES - A CASE-STUDY, Brain & development, 15(3), 1993, pp. 226-230
A study of epileptic drop attacks (EDA) by simultaneous video-polygrap
hic recordings was carried out in one epileptic patient with myoclonic
astatic seizures (Doose syndrome). EDA was shown to correspond to a b
urst of generalized bilaterally synchronous spike and wave complexes (
GBSSW) at 3 Hz. Absence seizures were also observed with a burst of GB
SSW with similar characteristics. The amplitudes of the corresponding
slow wave component of GBSSW among the three intensities of atonia, i.
e. complete atonia, minor atonia and no discernible atonia (control),
was compared. A high amplitude was demonstrated to correspond with mor
e pronounced atonia and a lower amplitude with reduced or absent atoni
a. These findings suggest that EDA corresponding to GBSSW have a neuro
physiological mechanism in common with absence seizures, and that if t
he GBSSW is intense, it may be sufficient to cause immediate loss of g
lobal muscle tone.