Seven hundred and twenty-seven renal transplant patients are reviewed
with respect to the occurrence of urinary tract infection (UTI) after
renal transplantation. UTI was defined as the detection of both bacter
iuria (10(5) CPU/ml) and pyuria (10 leukocytes/hpf). un developed in 1
1 of the inpatients (20.8%) and in 30 (4.2%) of the outpatients during
a one-year period. Among outpatients, 12 had symptomatic infections,
comprising seven with acute pyelonephritis and five with acute cystiti
s. Asymptomatic UTI was detected in 18 patients. In addition, asymptom
atic bacteriuria without pyuria was observed in ten (1.4%) patients. U
TI was more common in patients with diabetes, and underlying urinary t
ract complications were present in some patients. Administration of tr
imethoprim-sulfamethoxazole for about 4 months is suggested to reduce
the frequency of UTI in the early period after renal transplantation.