AUTOMATED VENTRICULAR TACHYARRHYTHMIA RECOGNITION - A COMBINATION OF CYCLE LENGTH AND NONLINEAR DYNAMICS MEASUREMENTS

Introduction: Cardiac monitoring devices such as external cardioverter defibrillators and ICU computerized ECC monitoring systems sense indi vidual QRS complexes to detect and subclassify ventricular tachyarrhyt hmias, Many algorithms that evaluate ECG morphology mark individual QR S complexes so that specific waveform characteristics can be measured, QRS sensors miss a percentage of electrogram events, especially durin g fibrillatory rhythms; thus, a morphology algorithm that helps subcla ssify arrhythmias without marking individual electrogram events may be more robust and improve arrhythmia detection accuracy. Methods and Re sults: Four nonlinear dynamics calculations were evaluated for detecti ng ventricular tachyarrhythmias and for subclassifying monomorphic ven tricular tachycardia (MVT) and polymorphic ventricular tachycardia (PV T), Five-second epochs of normal (NML, n = 48), MVT (n = 58), and PVT (n = 75) rhythms were presented to a statistical discriminant function based on cycle length (CL), and its performance was compared to two o ther discriminant functions, one consisting of the nonlinear dynamics calculations and one consisting of a combination of all variables, The discriminant function based on nonlinear dynamics calculations and CL detected 100% of the ventricular tachyarrhythmias, and subclassified more (P < 0.001) MVT and PVT arrhythmias (90 %) than that based on CL alone (71 %). Conclusions: The nonlinear dynamics measurements used in this study significantly increased the subclassification accuracy of the CL-based discriminant function, and they were calculated from ECG signals without marking individual QRS complexes, Therefore, arrhythmi a detectors that use nonlinear dynamics measurements may commit fewer classification errors due to QRS undersensing and aid therapy decision s when circumstances suggest that QRS sensing is inaccurate.