HERPES-SIMPLEX VIRUS TYPE-1 GENE-EXPRESSION IN GANGLIA INNERVATING THE HUMAN GASTROINTESTINAL-TRACT

Authors
GESSER RM KOO SC
Citation
Rm. Gesser et Sc. Koo, HERPES-SIMPLEX VIRUS TYPE-1 GENE-EXPRESSION IN GANGLIA INNERVATING THE HUMAN GASTROINTESTINAL-TRACT, Journal of virology, 71(5), 1997, pp. 4103-4106
Citations number
38
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
71
Issue
5
Year of publication
1997
Pages
4103 - 4106
Database
ISI
SICI code
0022-538X(1997)71:5<4103:HVTGIG>2.0.ZU;2-1
Abstract
Using in situ hybridization, we demonstrated that latent herpes simple x virus type 1 (HSV-1) gene expression is prevalent in human adult nod ose ganglia. This suggests that infection of gastrointestinal sensory nerves, probably through swallowed virus-laden oral secretions, occurs commonly and that HSV-1 reactivating from this site may play a role i n recurrent gastrointestinal disorders.