DNA STUDIES IN THE PROGNOSIS OF COLORECTA L-CANCER - RETROSPECTIVE ANALYSIS IN 34 PATIENTS

Citation
A. Bianchi et al., DNA STUDIES IN THE PROGNOSIS OF COLORECTA L-CANCER - RETROSPECTIVE ANALYSIS IN 34 PATIENTS, Revista espanola de enfermedades digestivas, 84(2), 1993, pp. 100-104
Citations number
NO
Categorie Soggetti
Gastroenterology & Hepatology
ISSN journal
11300108
Volume
84
Issue
2
Year of publication
1993
Pages
100 - 104
Database
ISI
SICI code
1130-0108(1993)84:2<100:DSITPO>2.0.ZU;2-6
Abstract
Objective We study the tumoral DNA as a pronostic factor in patients o perated for colo-rectal cancer. Design: Retrospective. We analize by f low cythometry the DNA content of tumoral tissue: Ploidy, DNA Index, P roliferative Index, S Phase. Patients. 34 operated patients, for colo- rectal cancer, whit a minimum 3 years of follow-up. Results. Ploidy do esn't show any relation whit other pronostic factors. Only Dukes C ane uploid patients had more positive nodes than diploid. Ploidy was not r elated to better evolution or survival. Neither DNA Index, Proliferati ve Index and S Phase were related to the evolution of the disease. Con clusions.- The DNA study by flow cythometry has no better pronostic va lue then other classical factors.