A. Bianchi et al., DNA STUDIES IN THE PROGNOSIS OF COLORECTA L-CANCER - RETROSPECTIVE ANALYSIS IN 34 PATIENTS, Revista espanola de enfermedades digestivas, 84(2), 1993, pp. 100-104
Objective We study the tumoral DNA as a pronostic factor in patients o
perated for colo-rectal cancer. Design: Retrospective. We analize by f
low cythometry the DNA content of tumoral tissue: Ploidy, DNA Index, P
roliferative Index, S Phase. Patients. 34 operated patients, for colo-
rectal cancer, whit a minimum 3 years of follow-up. Results. Ploidy do
esn't show any relation whit other pronostic factors. Only Dukes C ane
uploid patients had more positive nodes than diploid. Ploidy was not r
elated to better evolution or survival. Neither DNA Index, Proliferati
ve Index and S Phase were related to the evolution of the disease. Con
clusions.- The DNA study by flow cythometry has no better pronostic va
lue then other classical factors.