SUCCESSFUL FIBRINOLYTIC THERAPY USING TISSUE-PLASMINOGEN ACTIVATOR INACUTE-RENAL-FAILURE DUE TO ACUTE THROMBOSIS OF BILATERAL RENAL-ARTERIES

A 46-year-old housewife with regurgitation of mitral valve developed a cute renal failure due to acute thrombosis of bilateral renal arteries after cardiac catheterization. A regional fibrinolytic therapy using transarterial infusion of tissue plasminogen activator (t-PA) was perf ormed at 8 h after the onset, and was successful. She could be taken o ff hemodialysis 2 weeks after the fibrinolytic therapy, and could be s uccessfully operated on with mitral valve replacement 7 months after t hat. Three years after mitral valve replacement, her serum creatinine was 148 mumol/l. This is the longest follow-up case after regional tra nsarterial fibrinolysis of acute thrombosis of renal artery using t-PA , and this therapy is a safe and good one for acute thrombosis of rena l artery.