Yo. Chernoff et al., MULTICOPY SUP35 GENE INDUCES DE-NOVO APPEARANCE OF PSI-LIKE FACTORS IN THE YEAST SACCHAROMYCES-CEREVISIAE, Current genetics, 24(3), 1993, pp. 268-270
Previously, we have shown that plasmid-mediated multiplication of Sacc
haromyces cerevisiae wild-type SUP35 gene leads to omnipotent suppress
ion and is incompatible with psi-factor, which is an endogenous extrac
hromosomal suppressor. Here, we describe a frequent de-novo appearance
of psi-like factors in mitotic progeny of yeast transformants contain
ing multicopy SUP35 gene.