THE ISOLATION AND NUCLEOTIDE-SEQUENCE OF THE PYRUVATE DECARBOXYLASE GENE FROM KLUYVEROMYCES-MARXIANUS

Authors
HOLLOWAY P SUBDEN RE
Citation
P. Holloway et Re. Subden, THE ISOLATION AND NUCLEOTIDE-SEQUENCE OF THE PYRUVATE DECARBOXYLASE GENE FROM KLUYVEROMYCES-MARXIANUS, Current genetics, 24(3), 1993, pp. 274-277
Citations number
26
Categorie Soggetti
Genetics & Heredity
Journal title
Current genetics → ACNP
ISSN journal
01728083
Volume
24
Issue
3
Year of publication
1993
Pages
274 - 277
Database
ISI
SICI code
0172-8083(1993)24:3<274:TIANOT>2.0.ZU;2-9
Abstract
We have determined the nucleotide sequence of a 2360-basepair (bp) reg ion of the Kluyveromyces marxianus genome containing the structural ge ne for the enzyme pyruvate decarboxylase (PDC). Comparison of the dedu ced amino-acid sequence of this gene to that of the Saccharomyces cere visiae PDC genes reveals extensive homology including a motif common t o thiamin diphosphate-dependent enzymes.