Js. Madalengoitia et Tl. Macdonald, SYNTHESIS OF TETRAHYDROFUROCARBAZOLONES VIA INTRAMOLECULAR DIELS-ALDER REACTIONS, Tetrahedron letters, 34(39), 1993, pp. 6237-6240
l-3a,4,10,10a-tetrahydrofuro[3,4-b]carbazol-1-ones were synthesized by
an intramolecular Diels-Alder reaction. Exo/endo product ratios were
found to be sensitive to both solvent and temperature. The synthesis o
f isoelliptitoxin 2, a hybrid molecule of ellipticine and 4'-demethylp
odophyllotoxin, is presented.