The hypothesis that 6 months after acute myocardial infarction, adopti
on of secondary prevention activities would be higher, quality of life
better, and blood cholesterol lower in patients randomly allocated to
a mail-out intervention program than in those receiving usual care wa
s tested. Patients were aged < 70 years, admitted to hospitals in and
around Newcastle, Australia with a suspected heart attack and discharg
ed alive from the hospital. Cluster randomization, based on the patien
t's family practitioner, was used to allocate consenting patients to a
n intervention or usual care group. A low-cost mail-out program was de
signed to help patients reduce dietary fat, obtain regular exercise by
walking and (for smokers only) to quit smoking. Supplementary telepho
ne contact was also used. In addition, a letter was sent to the family
doctor regarding the benefit of aspirin and beta blockers for seconda
ry prevention. Of eligible patients, 71% participated, and 79% of the
213 intervention subjects and 87% of the 237 usual care ones returned
a 6-month follow-up questionnaire. Self-reported fat intake was signif
icantly lower, an ''emotional'' score obtained from a quality-of-life
questionnaire was significantly higher in the intervention than in the
usual care group, and ''physical'' and ''social'' scores for quality
of life were slightly higher. Blood cholesterol level and other variab
les were not different between the groups at 6 months. Simple low-cost
programs providing support and advice on lifestyle change may be bene
ficial, particularly in improving patients' perceived quality of life.