This paper significantly extends and generalizes the paragrassmann cal
culus of our previous paper [1]. Here we discuss explicit general cons
tructions for paragrassmann calculus with one and many variables. For
one variable, nondegenerate differentiation algebras are identified an
d shown to be equivalent to the algebra of (p + 1) x (p + 1) complex m
atrices. If (p + 1) is a prime integer, the algebra is nondegenerate a
nd so unique. We then give a general construction of many-variable dif
ferentiation algebras. Some particular examples are related to multi-p
arametric quantum deformations of the harmonic oscillators.