A. Nishiwaki et Jr. Bourne, ANALYSIS OF SUBSTRATE CONVERSION IN A BUBBLE-COLUMN BIOREACTOR WITH AMEMBRANE-FILTER FOR CONTINUOUS-CULTURE, Chemical engineering communications, 119, 1993, pp. 95-107
The steady-state performance, mainly with respect to substrate convers
ion, of a bubble column bioreactor with substrate limited microbial gr
owth and cell recycle through a membrane filter is investigated numeri
cally. The dispersion model and the Monod equation are employed for de
scribing flow behaviour and cell growth rate in the reactor, respectiv
ely. Moderate longitudinal mixing causes a favourable effect on the su
bstrate conversion. Such an effect is enhanced with increasing recycle
ratio and separator concentration efficiency. There exists an optimum
Peclet number to maximize the substrate conversion. The relation betw
een the critical recycle ratio at which the optimum Peclet number beco
mes zero and the corresponding exit substrate concentration is present
ed.