ANTIMICROBIAL PROPERTIES OF THE CONSTITUENTS OF PIPER ADUNCUM

Citation
Al. Okunade et al., ANTIMICROBIAL PROPERTIES OF THE CONSTITUENTS OF PIPER ADUNCUM, PTR. Phytotherapy research, 11(2), 1997, pp. 142-144
Citations number
14
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
ISSN journal
0951418X
Volume
11
Issue
2
Year of publication
1997
Pages
142 - 144
Database
ISI
SICI code
0951-418X(1997)11:2<142:APOTCO>2.0.ZU;2-8
Abstract
An ethanol extract of the leaves of Piper aduncum demonstrated good an timicrobial activity. Bioassay-directed fractionation of this extract led to the isolation of 4-methoxy-3,5-bis(3'-methylbenzoic acid) 1,2,6 -dihydroxy-4-methoxy-chalcone 2, nervogenic acid 3 and xy-8-(3-methyl- 2-butenyl)-2H-chromene-6-carboxylic acid 4. These compounds showed con siderable in vitro antifungal and antibacterial activity. (C) 1997 by John Wiley & Sons, Ltd.