Sb. Virchenko et al., THE DUODENOJEJUNAL JUNCTION AND TREITZ LIGAMENT IN THE REGULATION OF DUODENAL EMPTYING, Scandinavian journal of gastroenterology, 28(9), 1993, pp. 753-759
In chronic experiments in dogs the evacuatory and absorptive duodenal
functions and the level of duodenogastric reflux (DGR) in sham-operate
d dogs and dogs with transected Treitz ligament (TL) and resected duod
enojejunal junction (DJJ) were studied. The electrophysiologic charact
eristics of the antrum, duodenum, and DJJ in sham-operated dogs were e
xamined. It was shown that there is a coordination of gastric and duod
enal solid carbohydrate food emptying. The process of evacuation from
both organs was characterized by three closely correlated phases, phas
e 2 of emptying being exponential. In the TL transection and DJJ resec
tion groups the coordination of gastric and duodenal emptying disappea
red. The rate of carbohydrate solid food evacuation from the duodenum
decreased, on average, by 45.5% +/- 5.5% (P < 0.05); phase 2 of duoden
al emptying became unexponential, and the level of DGR considerably in
creased. The rate of duodenal absorption of main organic chyme compone
nts increased significantly in most of the time intervals studied. Sig
nificantly higher amplitudes of slow waves and spike potentials were r
ecorded from the DJJ than from the duodenum. We conclude that the DJJ
and TL are possible regulators of duodenal emptying. The DJJ is probab
ly a functional sphincter that provides coordinated activity of the st
omach and duodenum.