IDENTIFICATION OF AN ALLELIC VARIANT OF ISOFORM MLC1-V SB (HUMAN MYOSIN LIGHT-CHAIN)/

Authors
LAPTEV AV SHISHKIN SS KOVALYOV LI GALYUK MA MUSOLYAMOV AK EGOROV TA
Citation
Av. Laptev et al., IDENTIFICATION OF AN ALLELIC VARIANT OF ISOFORM MLC1-V SB (HUMAN MYOSIN LIGHT-CHAIN)/, Biochemical genetics, 31(5-6), 1993, pp. 253-258
Citations number
17
Categorie Soggetti
Genetics & Heredity",Biology
Journal title
Biochemical genetics → ACNP
ISSN journal
00062928
Volume
31
Issue
5-6
Year of publication
1993
Pages
253 - 258
Database
ISI
SICI code
0006-2928(1993)31:5-6<253:IOAAVO>2.0.ZU;2-Y
Abstract
A study of 250 specimens of human myocardium by two-dimensional gel el ectrophoresis revealed an allelic variant of isoform MLC1-V/sB, which was identified by immunoblotting with monoclonal antibody against MLC1 -V/sB and peptide mapping after in situ tryptic digestion of electrobl otted proteins. The substitution Asn-144 for His-144 was found in this new allelic variant of MLC1-V/sB.