Emm. Debrabandervandenberg et Ew. Meijer, POLY(PROPYLENE IMINE) DENDRIMERS - LARGE-SCALE SYNTHESIS BY HETEREOGENEOUSLY CATALYZED HYDROGENATIONS, Angewandte Chemie, International Edition in English, 32(9), 1993, pp. 1308-1311
In kilogram quantities; pure poly(propylene imine) dendrimers can be p
repared in an extremely simple reaction sequence comprising Michael ad
dition (primary amines to acrylonitrile) and heterogeneous hydrogenati
on with a Raney cobalt catalyst. Both steps proceed quantitatively and
selectively and can be employed with many core and end groups.