Sh. Cheng et al., MONOCYTE ANTIMYCOBACTERIAL ACTIVITY BEFORE AND AFTER MYCOBACTERIUM-BOVIS BCG VACCINATION IN CHINGLEPUT, INDIA, AND LONDON, UNITED-KINGDOM, Infection and immunity, 61(10), 1993, pp. 4501-4503
Monocytes from purified protein derivative S Mantoux-negative children
and young adults inhibited intracellular growth of Mycobacterium micr
oti more in Chingleput than in London. Mycobacterium bovis BCG vaccina
tion did not enhance bacteriostasis with the Indians but did so with t
he Londoners. No evidence was found for involvement of cytokines such
as macrophage-activating factor and granulocyte macrophage colony-stim
ulating factor in the differences.