RATIONALE AND OBJECTIVES. Duplex ultrasonography is currently used as
a noninvasive imaging modality for the functional evaluation of penile
blood flow in impotent men. However, the accuracy of this test is con
troversial. The objective of this study was to determine the sensitivi
ty and specificity of duplex ultrasonography, to assess the ultrasonog
raphic parameters most predictive of arterial disease, and to evaluate
the causes of misinterpretation of duplex ultrasound studies. METHODS
. Duplex ultrasonography and pudendal arteriography were performed on
42 impotent men during a 4-year prospective study. The predictive powe
r of the following ultrasonographic parameters were analyzed: cavernos
al arterial diameter, peak blood flow velocity, and pulsations on real
-time ultrasonography. RESULTS. The results of both studies were conco
rdant in 81 % of the patients with a 77 % sensitivity and 85 % specifi
city for ultrasonography when using arteriography as the gold standard
. Arterial pulsations and peak blood flow velocity were most predictiv
e, whereas dilation was not helpful. Variant penile arterial anatomy w
as present in 83% of the patients and was the most frequent cause of m
isinterpretation of duplex ultrasonography. CONCLUSION. Duplex ultraso
nography is a fairly reliable screening test for arterial disease in i
mpotent men. Visualization of arterial pulsations and measurement of p
eak blood flow velocity are the best predictors of arterial function.
Awareness of the potential arterial anomalies may help reduce misinter
pretation of ultrasonography. Arteriography is necessary in any patien
t being considered for penile arterial surgery because of the high fre
quency of anatomic variations.