Dj. Farrell et al., RAPID SCREENING OF CERVICAL SMEARS AS A METHOD OF INTERNAL QUALITY-CONTROL - FOR HOW LONG SHOULD WE RESCREEN, Acta cytologica, 41(2), 1997, pp. 251-260
OBJECTIVE: To compare the effectiveness of vapid screening of cervical
smears as a method of internal quality control with 10% random rescre
ening. STUDY DESIGN: From June 5 to July 14, 1995 (6 weeks), all conse
cutive cervical smears received in the department (n = 8,800) were ent
ered into the study and were prescreezed for a duration of 30 seconds
(n = 2,938), 1 minute (n = 2,925) or 2 minutes (n = 2,937) over a peri
od of 2 weeks each. RESULTS: Rapid screening of all negative and unsat
isfactory smears detected more cytologic abnormalities than would be e
xpected with 10% random rescreening. Thirty-second rapid screening of
all negative and unsatisfactory smears was more efficient in detecting
false negatives than screening a proportion of the smears for longer
periods of time. Rapid screening was also a very effective method of d
etecting severe cytologic abnormalities in unscreened smears, detectin
g over 90% of high grade lesions. CONCLUSION: Rapid rescreening of neg
ative and unsatisfactory cervical smears is recommended as a very effe
ctive method of internal quality control. It is superior to 10% random
rescreening in reducing the false negative rate. Thirty-second rapid
rescreening is the most efficient period for which smears should be sc
reened. Rapid screening of unscreened smears could be used as a means
of selecting patients for prompt referral when a laboratory backlog ex
ists.