COMPARISON OF THE SENSITIVITY OF SPUTUM AND BRUSH CYTOLOGY IN THE DIAGNOSIS OF LUNG CARCINOMAS

OBJECTIVE: To describe the role of sputum and brush cytology in the di agnosis of lung carcinoma and to elucidate the influence of tumor loca tion, histologic tumor type and stage on the sensitivity of both metho ds. STUDY DESIGN: Retrospective and performed on 415 lung cancer patie nts. Two hundred of them were investigated only by sputum collection, 119 only by brushing and 96 by both methods. RESULTS: The overall sens itivity of the sputum technique was 0.403 and that of the brush method 0.500, while a combination of both showed a sensitivity of 0.640. The diagnostic yield depended on tumor location, histologic tumor type an d stage. Sputum specimens were most valuable in the detection of early and peripheral carcinomas, whereas brushing was superior in finding m ore advanced and centrally located malignancies. Regarding tumor type, squamous cell carcinomas were diagnosed to the greatest extent by bot h methods. CONCLUSION: A complementary role of both cytologic techniqu es can be postulated by our data as well as by a literature review.