LACTIC-DEHYDROGENASE ACTIVITY AND LD-ISOENZYMES DISTRIBUTION IN THE SERUM OF PIGLETS WITH MYOCLONIA-CONGENITA

Serum lactic dehydrogenase (LD) and LD isoenzyme activities were studi ed in Prestice Black Pied breed pigs from a myoclonia congenita affect ed herd. The mean values of total LD activity for sows and boars were 9,8 +/- 0,5 mukat.l-1 and 5,9 +/- 0,6 mukat.l-1, respectively, while t he mean values of LD activity for affected and control group of piglet s were 13,7 +/- 0,2 mukat.l-1 and 9,5 +/- 0,5 mukat.l-1, respectively. Total serum LD level, LD-4 and LD-5 isoenzyme levels were found in hi gher concentrations (P < 0.01) in sows, while myoclonia congenita affe cted piglets showed significant (P < 0.01) increase in total LD enzyme and LD-5 isoenzyme activity. Positive correlation between myoclonia c ongenita and significantly elevated LD enzyme and LD-5 isoenzyme activ ity allow us to suggest that these two factors could be considered bio markers of myoclonia congenita in piglets.