BACKGROUND: Metastatic calcifications are currently an uncommon compli
cation in patients with end-stage renal disease due to improvements in
management of these patients. When present, however, calcifications m
ay mimic neoplastic growth and can undergo fine needle aspiration biop
sy (FNAB). CASE: A case of calcinosis cutis was diagnosed by FNAB in a
50-year-old male with a history of end-stage renal disease who presen
ted with a subcutaneous nodule in the right side of his neck. CONCLUSI
ON: The presence of histiocytes, foreign body-type giant cells and ref
ractile material (calcium crystals) in FNAB material is diagnostic of
calcinosis cutis in the proper clinical setting.