KERATIN-POSITIVE, EPITHELIAL MEMBRANE ANTIGEN-POSITIVE SOLITARY PELVIC TUMOR WITH ULTRASTRUCTURAL FEATURES OF LARGE-CELL LYMPHOMA

A case of an unusual malignant solitary pelvic tumor is presented. The neoplastic cells were positive for keratin and epithelial membrane an tigen. Although ultrastructural features (prominent nuclear pleomorphi sm, abundant polyribosomes, and absence of cell junctions) were those typically seen in large cell lymphomas, lymphoid markers were not dete cted, and immunoglobulin heavy-chain gene and T-cell receptor beta-cha in gene rearrangements were not identified. Combination chemotherapy r esulted in complete remission.