CYTOTOXIC PROTEIN FROM HUMAN PLATELETS

Authors
GOLUBEVA TS PAROMOV VM TUGUZ AR CHERTOV OY KISELEVSKY MV
Citation
Ts. Golubeva et al., CYTOTOXIC PROTEIN FROM HUMAN PLATELETS, FEBS letters, 405(3), 1997, pp. 312-314
Citations number
21
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
405
Issue
3
Year of publication
1997
Pages
312 - 314
Database
ISI
SICI code
0014-5793(1997)405:3<312:CPFHP>2.0.ZU;2-J
Abstract
The 14 kDa protein was purified from human platelets. It displays high cytotoxic activity to the human ACL cells at 10 M concentration (21.8 +/-7.1%). Its N-terminal sequence is YAPQXQFGP-, being highly homologo us to region 241-249 residues of the human Cls complement component. ( C) 1997 Federation of European Biochemical Societies.