EVIDENCE FOR SUSTAINED PLATELET ACTIVATION IN PATIENTS WITH EARLY POSTINFARCTION ANGINA

Authors
HOFMANN D HAMM CW LORENZ RL TERRES W WEBER PC
Citation
D. Hofmann et al., EVIDENCE FOR SUSTAINED PLATELET ACTIVATION IN PATIENTS WITH EARLY POSTINFARCTION ANGINA, Thrombosis research, 72(2), 1993, pp. 139-143
Citations number
15
Categorie Soggetti
Hematology,"Cardiac & Cardiovascular System
Journal title
Thrombosis research → ACNP
ISSN journal
00493848
Volume
72
Issue
2
Year of publication
1993
Pages
139 - 143
Database
ISI
SICI code
0049-3848(1993)72:2<139:EFSPAI>2.0.ZU;2-E
Abstract
Excretion of 2,3-dinor-thromboxane B2 released from activated platelet s has been found elevated in patients with acute myocardial infarction and unstable angina. To investigate the role of thrombotic activity i n postinfarction angina we measured urinary concentrations of 2,3-dino r-thromboxane B2 in 20 patients over 10 days after myocardial infarcti on. Compared with 11 patients recovering pain-free, excretion of 2,3-d inor-thromboxane B2 was found elevated in 9 patients who developed pos tinfarction angina. Accordingly, early postinfarction angina appears t o be associated with ongoing thrombotic activity.