J. Le et A. Gevins, METHOD TO REDUCE BLUR DISTORTION FROM EEGS USING A REALISTIC HEAD MODEL, IEEE transactions on biomedical engineering, 40(6), 1993, pp. 517-528
A mathematical procedure, which we call ''Deblurring,'' was developed
to reduce spatial blur distortion of scalp-recorded brain potentials d
ue to transmission through the skull and other tissues. Deblurring est
imates potentials at the superficial cerebral cortical surface from EE
G's recorded at the scalp using a finite element model of each subject
's scalp, skull and cortical surface constructed from their magnetic r
esonance images (MRI's). Simulations indicate that Deblurring is numer
ically stable, while a comparison of deblurred data with a direct cort
ical recording from a neurosurgery patient suggests that the procedure
is valid. Application of Deblurring to somatosensory evoked potential
data recorded at 124 scalp sites suggests that the method produces a
dramatic improvement in spatial detail, and merits further development
.