R. Koning et al., RESULTS OF BALLOON AORTIC VALVULOPLASTY IN PATIENTS WITH AORTIC-STENOSIS ASSOCIATED WITH SIGNIFICANT AORTIC REGURGITATION, Journal of interventional cardiology, 6(3), 1993, pp. 207-211
The influence of balloon aortic valvuloplasty (BA V) on aortic regurgi
tation (AR) in patients with severe aortic stenosis associated with gr
eater-than-or-equal-to grade II AR was studied by supraaortic angiogra
m before and after BA V. The results of 50 patients aged 72 +/- 12 yea
rs with significant AR before BA V (group A) were compared to 297 pati
ents (mean age 76 +/- 10 years) with no or mild AR (group B). In group
A, the patients had a higher left ventricular end diastolic volume (9
6 +/- 19 mL/m2 vs 81 +/- 32 mL/m2, P < 0.01) and left ventricular end
diastolic pressure (23 +/- 9 mmHg vs 19 +/- 9 mmHg, P < 0.01). The aor
tic valve area was similar in both groups. Following BAV, the improvem
ent in aortic valve area and hemodynamics were similar in both groups.
In group A, AR remained unchanged in 31 patients (62%), increased by
1 grade in 13 patients (26%), and decreased by 1 grade in 6 patients (
12%). In group B, AR increased by > 1 grade in 34 patients (11%) and >
2 grades in 4 patients (1.3%) post-BAV. Two patients in group B under
went emergency aortic valve replacement following BA V because of seve
re acute AR. In conclusion, when it is indicated, BAV can be performed
with similar risk in patients with significant AR.