R. Gorodetsky et al., TRACE-ELEMENT ANALYSIS OF LIPOSOMAL FORMULATIONS BY DIAGNOSTIC-X-RAY FLUORESCENCE SPECTROMETRY (DXS), Chemistry and physics of lipids, 64(1-3), 1993, pp. 31-34
Concentrations of Ca, Fe, Cu and Zn in liposomal doxorubicin were dete
rmined using diagnostic X-ray fluorescence spectrometry (DXS). No proc
essing of the liposomes was required. This method was applied successf
ully for quality control of different liposomal formulations.