INTERACTIONS BETWEEN SENSORY NEUROPEPTIDES AND LIPID MEDIATORS IN THEAIRWAYS

Authors
MANZINI S PERRETTI F MEINI S
Citation
S. Manzini et al., INTERACTIONS BETWEEN SENSORY NEUROPEPTIDES AND LIPID MEDIATORS IN THEAIRWAYS, Journal of lipid mediators, 8(2), 1993, pp. 67-79
Citations number
95
Categorie Soggetti
Biology
Journal title
Journal of lipid mediators → ACNP
ISSN journal
09218319
Volume
8
Issue
2
Year of publication
1993
Pages
67 - 79
Database
ISI
SICI code
0921-8319(1993)8:2<67:IBSNAL>2.0.ZU;2-1
Abstract
The local release of sensory neuropeptides from capsaicin-sensitive pr imary afferents elicits prominent motor and inflammatory actions in ma mmalian airways. This neurogenic inflammation can contribute to the pa thophysiology of asthma and airway hyperreactivity. In this review evi dence will be presented regarding the involvement of this peptidergic neural pathway in the mediation of some pulmonary actions of lipid med iators such as eicosanoids and PAF.