ISOLATION OF A RICKETTSIAL ORGANISM (EPERYTHROZOON) FROM MICE DURING VIROLOGICAL TESTING OF IXODID TICKS

Citation
Z. Hubalek et al., ISOLATION OF A RICKETTSIAL ORGANISM (EPERYTHROZOON) FROM MICE DURING VIROLOGICAL TESTING OF IXODID TICKS, Folia parasitologica, 40(2), 1993, pp. 157-159
Citations number
7
Categorie Soggetti
Parasitiology
Journal title
ISSN journal
00155683
Volume
40
Issue
2
Year of publication
1993
Pages
157 - 159
Database
ISI
SICI code
0015-5683(1993)40:2<157:IOARO(>2.0.ZU;2-C
Abstract
A strain of Eperythrozoon (Rickettsiales: Anaplasmataceae) was isolate d from suckling SPF mice (SM) inoculated with a homogenate of nymphal Ixodes ricinus (L.) ticks. The strain, passaged in the SM brain, was p artially filterable through a 220-nm Millipore membrane, moderately se nsitive to diethylether, and pathogenic for SM while no symptoms were observed in inoculated adult mice or male guinea pigs. A conspicuous c ytopathic effect was produced in PS and SPEV (embryo pig kidney) stabl e cell lines. Both the cell cultures and SM could be used for the infe ctivity titration of the agent.