Aw. Beardow et Jw. Buchanan, CHRONIC MITRAL-VALVE DISEASE IN CAVALIER KING CHARLES SPANIELS - 95 CASES (1987-1991), Journal of the American Veterinary Medical Association, 203(7), 1993, pp. 1023-1029
Systolic heart murmurs caused by chronic mitral valve disease are part
icularly common in Cavalier King Charles Spaniels (CKCS) in Great Brit
ain. To determine if American-bred CKCs have a similar high prevalence
of chronic valve disease, results of stethoscopic examinations on 394
CKCs were analyzed. Left apical systolic heart murmurs were found in
22% of the dogs. The prevalence ranged from 9% in dogs < 1 year old to
100% in those greater-than-or-equal-to 10 years old; prevalence was 5
6% in dogs greater-than-or-equal-to 4 years old. Differences were not
found in prevalence between sexes and among various coat colors. Reexa
mination of 79 dogs after 1 year revealed an incidence of new murmurs
of 21%. Comparison of ages at initial examination in 128 referral hosp
ital cases with chronic mitral valve disease revealed a mean age of 6.
25 years in 17 CKCs, in contrast to a mean age of 12 years in other br
eeds. Echocardiographic and necropsy findings indicated that ruptured
chordae tendineae and mitral valve prolapse are major components in th
e chronic valve disease process in CKCS.