68 disease free patients were investigated prospectively after jejunal
gastric replacement [jejunal interposition (JI): n=40; Roux en Y reco
nstruction (RY): n=28]. Used function tests were: scintigraphic emptyi
ng studies, hydrogene breath test, hepatobiliary sequential scintigrap
hy, oral glucose tolerance test, and upper intestinal manometry with 5
measuring ports (times of investigation: 6.-12. week and >1 year post
operatively). Patients with JI showed a better weight gain (p=0,001),
a lower reflux rate (p=0,01), a slower orocecal transit time (p=0,05),
a prompter bile flow after meal stimulation (p=0,02), and lower peak
glucose levels (p=0,001). The emptying patterns of the different gastr
ic substitutes were not different. A higher incidence of retrograde co
ntractions in RY and a electromechanical coordination between duodenum
and gastric substitute in JI were detected, We conclude that the post
operative function of the jejunal gastric substitute does not depend o
n it's emptying pattern or volume but on the motility patterns of the
entire intestinal tract which seem to be strongly influenced by the ch
oice of the jejunal reconstruction.