MULTIPLE INTRACRANIAL MELANOMA METASTASES TREATED WITH SURGERY AND RADIOSURGERY WITH LONG-TERM CONTROL - A CASE-REPORT

A case of malignant melanoma with multiplex brain metastases is descri bed, where both surgical and radiosurgical treatment was applied. Due to CNS manifestations the patient was operated on in two sessions. Fir st the symptomatic large tumor was removed, and the other, small lesio n which could not be reached from the same approach was operated later . The primary skin lesion was discovered and removed between the two o perations. A CT scan three months after the second operation revealed recurrence at the site of the first operation, and the appearance of t wo new tumors. The intracranial neoplasms were treated in one session by stereotactic radiosurgery using a linear accelerator. Six months af ter this treatment a new skin lesion was removed and the patient recei ved DTIC therapy. Successive CT scans after the irradiation showed a s teady regression of the radiosurgically treated tumors, and more than one year after the irradiation no tumor could be detected on the CT sc ans.