FERROCENE-ATTACHED L-LYSINE POLYMERS AS MEDIATORS FOR GLUCOSE-SENSINGELECTRODES

Two kinds of water-soluble polymers having ferrocenyl groups were prep ared by the reactions of ferrocenoyl chloride with a homopolymer and a copolymer of L-lysine. The polymers acted as electron mediators betwe en electrodes and the reduced form of glucose oxidase. Amperometric gl ucose-sensing electrodes were constructed by the simultaneous immobili zation of each polymeric mediator and glucose oxidase near the surface of a glassy carbon electrode with a semipermeable membrane. The sensi ng-electrode using the ferrocene-attached L-lysine homopolymer was usa ble for the determination of glucose concentrations up to 6 mM.