PREPARATION AND CHARACTERIZATION OF A MULTICYLINDER MICROELECTRODE COUPLED WITH A CONVENTIONAL GLASSY-CARBON ELECTRODE AND ITS APPLICATION TO THE DETECTION OF DOPAMINE
Wf. Peng et Ek. Wang, PREPARATION AND CHARACTERIZATION OF A MULTICYLINDER MICROELECTRODE COUPLED WITH A CONVENTIONAL GLASSY-CARBON ELECTRODE AND ITS APPLICATION TO THE DETECTION OF DOPAMINE, Analytica chimica acta, 281(3), 1993, pp. 663-671
A multi-cylinder microelectrode coupled with a conventional glassy car
bon disc electrode (MCM/GC) was prepared and characterized using cycli
c voltammetry and chronoamperometry. It was demonstrated that in the s
ame way as one observed a steady-state current at closely spaced micro
electrodes when redox recycling takes place, the same effect can be ob
tained with the MCM/GC device. The experimental results obtained with
K3Fe(CN)6 solutions were compared with a previously developed theory.
Further, it was demonstrated that with a carbon fibre MCM/GC device, t
he voltammetric behaviour of dopamine is greatly improved by virtue of
redox recycling, hence giving high sensitivity. The steady-state coll
ection current was linearly related to dopamine concentration in the r
ange 1 X 10(-4) to 5 x 10(-7) Mol l-1, and the detection limit was 2 x
10(-7) mol l-1. The influence of coexisting ascorbic acid was also in
vestigated. This device was applied successfully in the determination
of dopamine hydrochloride in pharmaceutical preparations.