ADVERSE EVENTS AND TREATMENT DISCONTINUATIONS IN FLUOXETINE CLINICAL-TRIALS

Authors
PANDE AC SAYLER ME
Citation
Ac. Pande et Me. Sayler, ADVERSE EVENTS AND TREATMENT DISCONTINUATIONS IN FLUOXETINE CLINICAL-TRIALS, International clinical psychopharmacology, 8(4), 1993, pp. 267-269
Citations number
6
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
International clinical psychopharmacology → ACNP
ISSN journal
02681315
Volume
8
Issue
4
Year of publication
1993
Pages
267 - 269
Database
ISI
SICI code
0268-1315(1993)8:4<267:AEATDI>2.0.ZU;2-C
Abstract
A re-analysis of the profile of adverse events observed in controlled clinical trials in summarized. The data confirm that the side-effects of fluoxetine therapy are different from those of the tricyclic antide pressants (TCAs), both in type and frequency. Moreover, the superior t olerability of fluoxetine compared with the TCAs is confirmed by the s ignificantly lower rate of premature discontinuation in the fluoxetine -treated patients than in the TCA-treated patients.