T. Petitclerc et al., A MODEL FOR NONINVASIVE ESTIMATION OF IN-VIVO DIALYZER PERFORMANCES AND PATIENTS CONDUCTIVITY DURING HEMODIALYSIS, International journal of artificial organs, 16(8), 1993, pp. 585-591
On-line monitoring of hemodialysis sessions requires a non-invasive es
timation of the parameters concerning the patient's status and the dia
lyzer performances. We describe here a model based on a new method for
non-invasive dialysance and patient conductivity measurements. In thi
s technique the same probe measures alternately the conductivity at th
e dialysate inlet and outlet for two different dialysate conductivity
values. From these data, an appropriate model allows to determine the
patient's conductivity as well as the effective dialysance of ionised
solutes, that is to say the dialysance corrected for recirculation. A
strong correlation is evidenced between the effective dialysance measu
red by this method and the urea clearance measured by conventional met
hods (r=0.98 for in vitro solutions; r=0.82 in in vivo situations).