Mc. Brodsky, THE PSEUDO-CSF SIGNAL OF ORBITAL OPTIC GLIOMA ON MAGNETIC-RESONANCE-IMAGING - A SIGNATURE OF NEUROFIBROMATOSIS, Survey of ophthalmology, 38(2), 1993, pp. 213-218
A five-and-a-half-year-old boy with neurofibromatosis had bilateral or
bital optic gliomas visible on magnetic resonance imaging. Both tumors
displayed a double-intensity signal characterized by a circumferentia
l area of CSF-intensity tissue surrounding and sharply delimited from
a central linear core of opposite signal intensity. The peripheral CSF
-intensity signal in orbital optic glioma correlates with the histopat
hological finding of perineural arachnoidal gliomatosis and serves as
a neuroradiologic marker for neurofibromatosis.