Eighty-one outpatients with bipolar disorder (BD) were grouped by SADS
anxiety symptom scores (high vs. low) or diagnosis of generalized anx
iety disorder, and/or panic disorder. BD patients with high anxiety sc
ores were more likely to have suicidal behaviour (44% vs. 19%), alcoho
l abuse (28% vs. 6%), cyclothymia (44% vs. 21%) and an anxiety disorde
r (56% vs. 25%) with a trend toward lithium non-responsiveness. Diagno
sis of an anxiety disorder was related only to high anxiety and lower
GAS scores. Thus, anxiety may have similar clinical relevance in BD as
it does in unipolar patients.