PREPARATION AND STRUCTURE OF A TETRASUBSTITUTED DERIVATIVE OF N''-CYANOGUANIDINE, N,N,N',N'-TETRABENZYL-N''-CYANOGUANIDINE

A tetrasubstituted derivative of N''-cyanoguanidine (CG), N,N,N',N'-te trabenzyl-N''-cyanoguanidine (TBCG), was prepared by a phase-transfer reaction of CG with benzyl chloride in a 25% (w/w) NaOH aq soln-dichlo romethane using tetrabutylammonium hydrogensulfate as a catalyst. TBCG was identified by means of an elemental analysis, H-1- and C-13 NMR s pectroscopy, FD mass spectrometry and an X-ray crystal analysis. The c rystal is monoclinic, space group P2(1)/n, a=10.231 (2), b=14.158 (4), c=17.231 (4) angstrom, beta=95.27 (4)degrees, V=2483 (1) angstrom3, Z =4, D(c)=1.189 g cm-3, mu (Mo Kalpha)=0.66 cm-1. The final R value was 0.069 for 1196 reflections.