EFFICACY OF A SYNTHETIC MESH SLING IN KEEPING THE SMALL-BOWEL IN THE UPPER ABDOMEN TO PREVENT RADIATION ENTEROPATHY IN GYNECOLOGIC MALIGNANCIES

Citation
Ym. Vankasteren et al., EFFICACY OF A SYNTHETIC MESH SLING IN KEEPING THE SMALL-BOWEL IN THE UPPER ABDOMEN TO PREVENT RADIATION ENTEROPATHY IN GYNECOLOGIC MALIGNANCIES, European journal of obstetrics, gynecology, and reproductive biology, 50(3), 1993, pp. 211-218
Citations number
29
Categorie Soggetti
Reproductive Biology","Obsetric & Gynecology
ISSN journal
03012115
Volume
50
Issue
3
Year of publication
1993
Pages
211 - 218
Database
ISI
SICI code
0301-2115(1993)50:3<211:EOASMS>2.0.ZU;2-F
Abstract
Radiation therapy in gynecological malignancies is limited by the freq uent occurrence of radiation enteropathy at effective dose levels of 4 5 Gy and higher. Elevation of the small bowel out of the true pelvis s hould enable doses of up to 60-70 Gy to be given without damaging the small bowel. We report a feasibility study concerning elevation of the small bowel out of the true pelvis, by creating an intra-abdominal sl ing with a synthetic mesh. Twelve patients with pelvic gynecological m alignancies were included since 1986. In all patients peroperative app lication of the mesh was possible. In ten patients adequate elevation of the small bowel was achieved. Two patients showed a right-sided her niation of a small bowel loop on a control barium opacification, perfo rmed 1 week postoperatively. In one of these a fistula occurred after resecuring the mesh. The most important problem in this study, as has also been reported elsewhere, was a herniation of a small bowel loop. The incidence is probably inversely correlated with the skill of the s urgeon and will therefore be reduced with increasing experience. Futur e long-term studies should address the issue whether or not radiation enteropathy can be prevented by this method.