DIASTEREOSELECTIVE ADDITION OF ORGANOCUPRATES ON 1,4-DIHYDROPYRIDINE-3-CARBOXALDEHYDES - SYNTHESIS OF CHIRAL 1,4-DIHYDROPYRIDYL-3-ALCOHOLS AND PYRIDYL-3-ALCOHOLS

Authors
MANGENEY P GOSMINI R RAUSSOU S COMMERCON M
Citation
P. Mangeney et al., DIASTEREOSELECTIVE ADDITION OF ORGANOCUPRATES ON 1,4-DIHYDROPYRIDINE-3-CARBOXALDEHYDES - SYNTHESIS OF CHIRAL 1,4-DIHYDROPYRIDYL-3-ALCOHOLS AND PYRIDYL-3-ALCOHOLS, Tetrahedron letters, 34(40), 1993, pp. 6399-6402
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
40
Year of publication
1993
Pages
6399 - 6402
Database
ISI
SICI code
0040-4039(1993)34:40<6399:DAOOO1>2.0.ZU;2-2
Abstract
Chiral 1,4-dihydropyridyl-3-alcohols are obtained via a diastereoselec tive (de 90% -> 95%) 1,2 addition of organocuprates on chiral 1,4-dihy dropyridine-3-carboxaldehydes and are transformed into chiral pyridyl- 3-alcohols (90% -> 95%).