Post-bulbar ulceration is uncommon, but a pilot study in Hyderabad sho
wed a high incidence. We therefore carried out a prospective endoscopi
c study of the distribution of peptic ulceration and its relation to s
ymptoms and demography. Of the 360 consecutive patients referred for e
ndoscopy, 113 (92 men, 21 women) had peptic ulceration. Median age 35
years, median duration one year. Five patients (4%) had gastric ulcer,
77 (68%) had duodenal ulcer, and 31 (28%) had coexisting gastric and
duodenal ulcer. The duodenal ulcer was found in the pyloric canal in 1
4% of patients, in the bulb in 80%, and the post-bulbar region in 56%
of patients. Sixty seven per cent of duodenal ulcers were located at m
ore than one site. The incidence of post-bulbar v bulbar ulcer was 1:1
.5. Deformed bulb was seen in 50% of duodenal ulcer patients, but haem
orrhage and stenosis were uncommon. Except for nocturnal pain, there w
ere no differences in symptoms between the groups. Forty two per cent
of patients smoked, 15% chewed tobacco, and 18% drank alcohol; almost
all were men. Sixty four per cent drank tea. The staple diet (85%) was
rice, and 70% used tamarind and spices daily. Duodenal ulcer was thre
e times more common than gastric ulcer with a high incidence of post-b
ulbar and coexisting ulcer. It affected a younger and predominantly ma
le population, and was not associated with a higher rate of complicati
on.