W. Hanggi et al., HOMOLOGOUS INTRAUTERINE INSEMINATION FOR TREATMENT OF ANDROLOGICAL INFERTILITY, Geburtshilfe und Frauenheilkunde, 53(9), 1993, pp. 635-640
In a two-years period, we treated 58 infertile couples for a total of
213 cycles with artificial homologous insemination (AIH). We considere
d a indication for AIH low sperm quality or a pathological postcoital
test (PCT). Couples with idiopathic infertility did not receive AIH. I
f possible, AIH was performed by intrauterine insemination (IUI), foll
owing concentration of the motile sperms by ''swim-up'' method. Out of
213 cycles ''swim-up'', preparation could not be done in 46 cases (21
.6 %) because the initial sperm quality was below technical limits (sp
erm count below 1 Mio/ml). Out of 58 treated couples 4 became pregnant
during AIH therapy (7 %) among, them 2 couples conceiving twice after
spontaneous early abortion. The total pregnancy rate per cycle was 2.
8 %. In the cycles after ''swim-up'', the monthly pregnancy rate throu
gh IUI was 3.6 %. In the presence of andrological factors was the preg
nancy rate only 0.9 % compared to 6.8 % in cases of pathological PCT w
ith normal sperm quality. Thus, it can be concluded, that IUI is not s
uccessful on the basis of low sperm quality. Only in cases of unfavour
able cervical factor expressed by a pathological PCT accompanied with
a normal spermiogramm, moderate success can be expected.