Aims: To highlight the different changes induced in lung tissues by va
rious forms of radiotherapy (RT) according to tumor site and type. Met
hods: A retrospective analysis of the roentgenographic evaluation of a
nd long-term follow-up data on 2375 patients who received RT for vario
us intrathoracic and extrathoracic tumors at the National Cancer Insti
tute of Milan. Results: The iconographic patterns of post-RT changes,
grouped by site and type of tumor and RT procedure and described in de
tail, afford deeper insight into a little-known area of lung pathology
. Conclusions: These descriptions of common and uncommon patterns of t
he irradiated lung as they appear on conventional chest roentgenograms
enable the radiologist and radiotherapist to assess exactly the respo
nse of tumor and lung tissues and to plan the most appropriate clinica
l follow-up.