A moderately differentiated neuroendocrine carcinoma of the larynx is
described. Although the patient had normal serum calcitonin level 36 m
onths before, its level was elevated at the time the neck node was rem
oved. This study supports the hypothesis that a diagnosis of calcitoni
n-producing neuroendocrine tumor of the larynx with increased plasma c
alcitonin is possible and should be considered to avoid unnecessary th
yroidectomy.