An experimental, placebo-controlled study with rabbits was conducted t
o determine the role of Abana, an Ayurvedic preparation, on atheroscle
rosis. The results showed that Abana arrested the rise in TC, LDLc and
VLDLc when administered along with an atherogenic diet for 60 days. I
n another phase of the study, when Abana was given from days 60-120 to
rabbits who were made hyperlipidemic by feeding them an atherogenic d
iet for 60 days, Abana brought the-TC, LDLc and VLDLc levels back to n
ormal. On the other hand, the levels of the cardioprotective HDLc were
elevated by Abana administration in both phases of the study. Histolo
gical pictures showed pronounced reduction in the atherosclerotic invo
lvement of the coronary artery following treatment with Abana. The arc
hitecture of the coronary artery returned almost to normal. These find
ings substantiate the possible role of Abana in the reduction, prevent
ion and reversal of atherosclerosis.